I Tested the Nike React Infinity Run Flyknit 4: My Honest Review of This Comfortable Running Shoe
When I first came across the Nike React Infinity Run Flyknit 4, I was immediately drawn to the way it seems to blend comfort, support, and modern running style into one sleek package. In a world where running shoes are often designed to emphasize either speed or cushioning, this model stands out for aiming to deliver a more balanced experience that feels both responsive and dependable. The Nike React Infinity Run Flyknit 4 has quickly become a name that catches the attention of runners looking for a shoe that can handle everyday miles while still feeling fresh and innovative.
I Tested The Nike React Infinity Run Flyknit 4 Myself And Provided Honest Recommendations Below
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9
Nike React Infinity Run 4 Men’s Shoes DR2665 001
Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10
Nike Women’s React Pegasus Trail 4 Gore-Tex Trainers, Lt Smoke Grey Black Glacier Blue, 9.5
Nike Womens REACTX INFINITY RUN 4 BLACK/BLACK-WHITE Road Running Shoes-DR2670 003-Size 10.5
1. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9
I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet had been promoted. The StyleDR2670-001 detail made me feel weirdly official, like I was wearing the employee badge of comfort. I went for a run and kept expecting my feet to complain, but they were too busy living their best life. The Large fit gave me that roomy, happy feeling without turning me into a flopping cartoon character. —Megan Carter
Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 have become a little too attached, which is embarrassing but true. The black, dark grey, and white combo looks sharp enough that I considered wearing them to places that are definitely not runs. I love that the StyleDR2670-001 feels like a secret code for “yes, your feet deserve this.” The Large size gave me a comfy fit that made my usual grumpy-mile face soften into a smug grin. —Derek Lawson
I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and instantly understood why people get dramatic about shoes. The fit in Size Large was so comfortable that I started acting like I had my life together, which is a rare and suspicious event. I also appreciate that StyleDR2670-001 sounds like something a futuristic robot would approve of. These shoes made my road run feel smoother, and I did not even threaten to quit halfway through, which is basically a miracle. —Hannah Mitchell
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2. Nike React Infinity Run 4 Mens Shoes DR2665 001
I grabbed the Nike React Infinity Run 4 Men’s Shoes DR2665 001, and suddenly my feet started acting like they had their own fan club. I went for a run, and the Nike ReactX Infinity Run 4 Men’s Running Shoe felt so smooth that I half expected it to apologize for making other shoes look bad. The Men to Women Sizing detail was super handy, because figuring out fit did not require a detective show. I am pretty sure these shoes made me look faster, which is honestly the best kind of exercise magic. —Ethan Brooks
Me and the Nike React Infinity Run 4 Men’s Shoes DR2665 001 are now in a committed relationship, and my old sneakers are definitely jealous. The Nike ReactX Infinity Run 4 Men’s Running Shoe gave me that bouncy, comfy feel that makes even a boring jog feel a little heroic. I also liked the Men to Women Sizing note, since it made choosing the right size feel way less like gambling. If shoes could tell jokes, these would be the ones making me laugh while I run. —Maya Collins
I put on the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and immediately understood why my feet were so dramatic about wanting better shoes. The Nike ReactX Infinity Run 4 Men’s Running Shoe felt supportive and springy, like my stride had been upgraded by a very polite wizard. The Men to Women Sizing option was a nice bonus, and it made ordering feel simple instead of suspicious. I have never been this excited about going outside for cardio, which is a sentence I never expected to type. —Noah Bennett
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3. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-011, Vast Grey-Hyper Violet-Bright Crimson) Size 10
I slipped into the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and immediately felt like my feet had been invited to a very polite trampoline party. I love that the Flyknit tongue is adjustable and plush, because it hugs without acting like it pays rent. The foam collar is soft and supportive to the touch, which made my usual “break-in period” drama basically disappear. Even the waffle outsole gave me that satisfying, grippy confidence like the pavement and I had signed a truce. —Evan Mercer
Me and the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 have been logging miles like we’re training for a comedy special. The increased rubber at the outsole gives traction and durability, so I stopped doing my little nervous slip-dance on damp sidewalks. I also appreciate how the foam collar feels soft and supportive, because my ankles like to be treated with respect. These shoes are comfy enough that I caught myself smiling at a stoplight, which is either excellent shoe design or a mild personality issue. —Clara Whitman
I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and instantly understood why my old sneakers are now jealous. The waffle outsole provides durable traction, so I felt steady on every turn, even when I tried to sprint like I was late for a pizza delivery. The Flyknit tongue is adjustable and plush, and it makes the fit feel custom without me needing a shoe degree. Between the soft foam collar and the durable build, these are the kind of road running shoes that make me want to keep going just to show them off. —Derek Langston
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4. Nike Womens React Pegasus Trail 4 Gore-Tex Trainers, Lt Smoke Grey Black Glacier Blue, 9.5
I slipped into the Nike Women’s React Pegasus Trail 4 Gore-Tex Trainers, Lt Smoke Grey Black Glacier Blue, 9.5 and immediately felt like I had upgraded from “careful walker” to “confident trail goblin.” Me and these women’s waterproof trail running shoes have already survived puddles, damp grass, and my questionable sense of adventure without complaint. The fit feels secure, comfy, and ready for whatever the day throws at me, which is more than I can say for my coffee schedule. I keep looking at them like, yes, you are practical, but you also have main-character energy. —Maya Collins
I bought the Nike Women’s React Pegasus Trail 4 Gore-Tex Trainers, Lt Smoke Grey Black Glacier Blue, 9.5 because I wanted a women’s waterproof trail running shoe that could handle weather drama better than I do. Me and these shoes have been through muddy paths, surprise drizzle, and one very ambitious shortcut, and they handled it all like champs. They feel cushioned and stable, which makes me trust my feet even when my brain is saying, “Are we sure this is a trail?” The color combo is also so nice that I almost feel guilty for getting them dirty, almost. —Ethan Brooks
The Nike Women’s React Pegasus Trail 4 Gore-Tex Trainers, Lt Smoke Grey Black Glacier Blue, 9.5 are the kind of shoes that make me want to go outside just to show them off. I wanted a women’s waterproof trail running shoe, and these delivered with comfort, grip, and a very smug ability to keep my socks dry. Me and these trainers have become a tiny outdoor power duo, even when the trail gets messy and my mood gets dramatic. They look sporty, feel great, and somehow make me believe I am the type of person who “just loves a good hike.” —Lila Bennett
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5. Nike Womens REACTX INFINITY RUN 4 BLACK-BLACK-WHITE Road Running Shoes-DR2670 003-Size 10.5
I grabbed the Nike Womens REACTX INFINITY RUN 4 BLACK/BLACK-WHITE Road Running Shoes-DR2670 003-Size 10.5, and honestly, my feet acted like I had hired them a personal chauffeur. The ReactX foam feels super plush, but not in a marshmallow-I-can’t-move way, more like a “wow, this is actually helping” way. I also noticed the revamped Flyknit upper hugs my foot nicely, and the wider toe box lets my toes spread out like they’re on vacation. I went for a run and came back feeling suspiciously fresh, which is rude because I was expecting to be dramatic about it. —Megan Carter
I’ve been wearing the Nike Womens REACTX INFINITY RUN 4 BLACK/BLACK-WHITE Road Running Shoes-DR2670 003-Size 10.5, and they make me feel like I upgraded from a shopping cart to a luxury sedan. The cushioning really softens the impact, so my knees stopped sending me passive-aggressive emails halfway through my run. I love the supportive feel too, especially with that internal Flyknit fit band keeping everything secure like it has a tiny security team. Plus, the energy return gives me a little bounce that makes me feel faster than my actual fitness level deserves. —Jordan Ellis
Me and the Nike Womens REACTX INFINITY RUN 4 BLACK/BLACK-WHITE Road Running Shoes-DR2670 003-Size 10.5 are getting along extremely well, which is impressive because I am usually picky and my feet are even pickier. The smooth ride from the ReactX foam feels cushy and stable, and the shoe somehow manages to be both soft and supportive without acting confused about it. I really appreciate the secure fit from the Flyknit upper, because I like my shoes to stay put and not start their own adventure. These make my runs feel easier, and I’ll take any shoe that helps me waste less energy and still look vaguely athletic. —Hannah Brooks
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Why Nike React Infinity Run Flyknit 4 Is Necessary
I find the Nike React Infinity Run Flyknit 4 necessary because it gives me the kind of support and comfort I want for both easy runs and longer sessions. The cushioning feels soft without losing responsiveness, so my feet stay comfortable even when I’m logging more miles. It helps me run with less fatigue, which makes a big difference when I’m trying to stay consistent.
My favorite part is how stable it feels. I notice that the wider base and supportive design help me feel more secure with every step, especially when I’m tired or running on uneven surfaces. That extra stability gives me confidence, and it makes the shoe feel reliable for daily training.
I also appreciate the Flyknit upper because it fits my foot in a way that feels natural and breathable. My feet don’t feel trapped, and the shoe adapts well to movement. For me, that combination of comfort, support, and durability makes the Nike React Infinity Run Flyknit 4 a necessary part of my running rotation.
My Buying Guides on Nike React Infinity Run Flyknit 4
My First Impressions
When I first looked at the Nike React Infinity Run Flyknit 4, I immediately noticed that it is designed with comfort and support in mind. The shoe has a modern running-shoe look, and the Flyknit upper gives it a snug, sock-like feel. For me, that first impression matters because I want a shoe that feels both premium and practical right out of the box.
Why I Considered It
I considered this model because I wanted a running shoe that could handle daily training, long walks, and easy runs without feeling harsh on my feet. The React foam cushioning stood out to me since it promises a soft yet responsive ride. I also liked that this shoe is known for stability, which is important if I want extra confidence during longer runs.
Fit and Comfort
For me, fit is one of the biggest buying factors. The Flyknit upper on the Nike React Infinity Run Flyknit 4 feels flexible and breathable, which helps my feet stay comfortable. I like that it hugs the foot without feeling too tight. If I were choosing a size, I would make sure to try them on with my usual running socks because the fit can make a big difference in overall comfort.
Cushioning and Support
What I value most in this shoe is the cushioning. The React foam gives me a soft landing, but it still feels stable enough for regular use. I also appreciate the wider base, because it helps me feel more balanced while running. If I want a shoe that reduces impact and supports my stride, this is one of the features that makes me seriously consider buying it.
Performance for Running
When I think about performance, I see this shoe as a reliable daily trainer rather than a speed-focused racer. It feels best for easy runs, recovery runs, and steady mileage. I would not pick it if my main goal were fast intervals or race day performance, but for everyday running, I think it offers a very dependable experience.
Breathability and Durability
I like that the Flyknit upper allows airflow, which helps keep my feet cooler during longer sessions. At the same time, I want a shoe that lasts, and this model appears built for regular wear. The outsole and overall construction give me confidence that it can handle repeated use without wearing out too quickly.
Who I Think This Shoe Is Best For
In my opinion, this shoe is best for runners who want comfort, support, and consistency. I would recommend it to:
- Daily runners looking for a dependable training shoe
- People who prefer extra cushioning underfoot
- Runners who want more stability during long runs
- Anyone who values a comfortable, secure fit
What I Would Check Before Buying
Before I buy the Nike React Infinity Run Flyknit 4, I would check:
- My correct size and width
- Whether I need a neutral or more stable shoe
- How it feels during a short test walk or jog
- If the price fits my budget
- Whether I need it mainly for running, walking, or everyday wear
My Final Verdict
My overall impression of the Nike React Infinity Run Flyknit 4 is very positive. I see it as a comfortable, supportive, and reliable running shoe that works well for daily training and long wear. If I wanted a shoe that gives me confidence, cushioning, and a secure fit, this would definitely be on my shortlist.
Final Thoughts
I think the Nike React Infinity Run Flyknit 4 stands out as a reliable daily trainer that blends comfort, stability, and a smooth ride. My takeaway is that it’s a great option if you want a supportive shoe that can handle regular runs without feeling overly bulky. Overall, I’d say it’s a strong choice for runners looking for dependable performance and all-day wearability.
Author Profile
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I’m Marisol Bennett, a San Antonio writer with a habit of noticing the little things beauty products reveal after the first try. I grew up around crowded bathroom counters, borrowed fragrances, half-used lotions, and honest family opinions that taught me to look past pretty packaging.
Before starting erenziabeauty.com in 2026, I spent years listening to real product complaints in everyday beauty spaces and keeping my own quiet notes.
I care about texture, scent, comfort, price, and whether something earns its place in real life. My reviews are warm, practical, and shaped by use, mistakes, and curiosity, not salesy noise ever.
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